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Other Specialized Reagents

Ethyl R-mandelate

Category:

Other Specialized Reagents

CAS NO:

10606-72-1

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

10606-72-1

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

Ethyl R-mandelate is a specialized chiral ester widely utilized in the pharmaceutical and fine chemical industries as a critical intermediate for asymmetric synthesis. Chemically identified by the CAS number 1567-23-9, this compound features the molecular formula C9H10O3 and possesses a specific optical rotation characteristic of its (R)-enantiomer configuration. Its structure consists of an ethyl group attached to the hydroxyl moiety of mandelic acid, preserving the chiral center at the benzylic carbon which is essential for its biological activity and synthetic utility. The primary application of Ethyl R-mandelate lies in its role as a chiral building block for the production of various bioactive compounds. It serves as a precursor in the synthesis of potent pharmaceutical agents, including antibiotics, antiviral drugs, and anti-inflammatory medications where stereochemical purity is paramount. Due to the strict regulatory requirements regarding enantiomeric excess in modern drug development, suppliers of high-purity Ethyl R-mandelate are in high demand to ensure the efficacy and safety of final therapeutic products. Furthermore, it is employed in the manufacturing of agrochemicals and fragrances, where specific molecular shapes dictate interaction with biological targets or olfactory receptors. In laboratory settings, this reagent is frequently used as a resolving agent to separate racemic mixtures into their individual enantiomers through diastereomeric salt formation or enzymatic resolution processes. Its relatively stable nature under standard storage conditions makes it convenient for handling, though it should be protected from strong oxidizing agents and stored in a cool, dry environment to prevent hydrolysis back into mandelic acid and ethanol. As the global demand for chiral drugs continues to expand, Ethyl R-mandelate remains a cornerstone material in organic synthesis, bridging the gap between simple precursors and complex, life-saving medicines. Researchers rely on its predictable reactivity and high optical purity to design efficient synthetic pathways that minimize waste and maximize yield in the creation of next-generation therapeutics.