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Other Specialized Reagents

Ethyl (R)-3-hydroxybutyrate

Category:

Other Specialized Reagents

CAS NO:

24915-95-5

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

24915-95-5

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

Ethyl (R)-3-hydroxybutyrate, chemically known as ethyl (R)-3-hydroxybutanoate, is a valuable chiral ester widely utilized in the fields of organic synthesis and pharmaceutical research. Its molecular formula is C6H12O3, and it carries the CAS registry number 79498-58-5. This compound serves as a critical building block for the asymmetric synthesis of various biologically active molecules due to its specific stereochemical configuration at the C3 position. The (R)-enantiomer is particularly significant because biological systems often exhibit high stereoselectivity, meaning that only one specific enantiomer may possess the desired therapeutic effect while the other could be inactive or even harmful. In the pharmaceutical industry, this molecule acts as a key intermediate in the production of statins, which are cholesterol-lowering drugs, and other complex natural products containing beta-hydroxy ester motifs. It is frequently employed as a starting material for preparing chiral ligands, catalysts, and advanced intermediates used in the total synthesis of polyketides. Furthermore, Ethyl (R)-3-hydroxybutyrate finds applications in the fragrance and flavor sectors, where it contributes specific fruity or dairy-like notes, although its primary industrial value remains rooted in fine chemical manufacturing. The compound is typically produced through enzymatic resolution processes or asymmetric hydrogenation, ensuring high optical purity which is essential for regulatory compliance in drug development. Researchers rely on its stability and reactivity profile to construct more complex carbon skeletons with precise stereocontrol. As the demand for enantiopure compounds grows in modern medicine, the role of Ethyl (R)-3-hydroxybutyrate becomes increasingly prominent. It facilitates the efficient creation of molecules that target specific receptors, thereby enhancing drug efficacy and safety profiles. Whether used in academic laboratories for mechanistic studies or in large-scale industrial settings for API synthesis, this versatile ester stands as a cornerstone in the toolkit of synthetic chemists aiming to develop next-generation therapeutics. Its unique properties make it an indispensable resource for advancing the frontiers of stereochemistry and medicinal chemistry globally.