1,2-Dithiolane-3-pentanoicacid,ethylester;EthylLipoicate;ThiocticAcidImpurity21;ethyl5-(1,2-dithiolan-3-yl)peChemicalbookntanoate;ThiocticAcidImpurity15;LIPOICACIDETHYLESTER;ThiocticAcidethylester;ethyl5-(dithiolan-3-yl)pentanoate
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<h3>Overview</h3>
<p>Ethyl Lipoicate Impurity refers to non-active chemical variants in the synthesis of ethyl lipoate, a key intermediate for pharmaceuticals. The primary synthetic route involves esterification of alpha-lipoic acid with ethanol under acidic catalysis. Molecular formula is C12H20O3S. CAS number is typically associated with specific impurity profiles rather than the parent compound alone.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Used as reference standards for HPLC purity testing during drug development.</li>
<li><strong>Quality Control:</strong> Essential for validating separation methods in API production facilities.</li>
<li><strong>Research & Development:</strong> Studied to optimize reaction pathways and minimize byproduct formation.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly limit clinical use to approved active ingredients; impurities must remain below ICH Q3A thresholds. Store in cool, dry environments away from oxidizing agents. Personnel must wear appropriate PPE including gloves and goggles due to potential skin irritation risks.</p>