*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Estrone-d4 is a <strong>stable isotopically labeled internal standard</strong> used in quantitative mass spectrometry. Synthesized via catalytic deuteration of natural estrone, it matches the physicochemical properties of the native analyte. Molecular Formula: C<sub>18</sub>H<sub>20</sub>O<sub>2</sub>D<sub>4</sub>; CAS No.: 5967-62-6.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Analysis:</strong> Quantification of endogenous estrone in bioequivalence studies.</li>
<li><strong>Clinical Diagnostics:</strong> Calibration for monitoring estrogen levels in patient serum.</li>
<li><strong>Metabolic Research:</strong> Tracing metabolic pathways and clearance rates in vivo.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent degradation. Strictly for research use only; not approved for clinical administration. Handle with appropriate PPE to avoid inhalation or skin contact.</p>