*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Doxycycline-d3 Hyclate (Major)</strong> is a deuterium-labeled internal standard for Doxycycline hyclate, synthesized via isotopic exchange. It features the molecular formula C22H25D3ClN2O8 and CAS No. 106984-73-2.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Analysis:</strong> Serves as a reference standard in LC-MS/MS quantification of doxycycline residues.</li>
<li><strong>Clinical Research:</strong> Validates pharmacokinetic studies and bioequivalence assessments.</li>
<li><strong>Quality Control:</strong> Ensures accuracy in stability-indicating methods for antibiotic formulations.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent degradation. Handle with appropriate PPE; avoid direct contact as it is a research chemical not intended for human administration.</p>