*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Dibutyl Phosphate-d18 is a deuterated isotopologue of dibutyl phosphate, primarily synthesized via the esterification of phosphoric acid with deuterated butanol. It serves as a critical <strong>internal standard</strong> in mass spectrometry for quantitative analysis. The molecular formula is C<sub>8</sub>H<sub>12</sub>D<sub>18</sub>O<sub>4</sub>P, and its CAS number is 100657-99-8.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Analysis:</strong> Used to quantify drug metabolites in pharmacokinetic studies.</li>
<li><strong>Metabolomics:</strong> Enables precise tracking of metabolic pathways using LC-MS/MS.</li>
<li><strong>Quality Control:</strong> Validates assay accuracy in bulk active pharmaceutical ingredient testing.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at controlled temperatures below 25°C. Handle with appropriate PPE to avoid skin contact; do not use in clinical settings directly as it is a research reagent only.</p>