*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Cotinine N-Beta-D-Glucuronide is a major metabolite of nicotine, utilized as a certified reference standard in toxicology. Produced via enzymatic conjugation or semi-synthesis, it serves as a biomarker for tobacco exposure. <strong>Molecular Formula</strong>: C16H24N2O7; <strong>CAS No.</strong>: 1098-53-9.</p>
<h3>Application</h3>
<ul>
<li><strong>Toxicological Screening</strong>: Quantitative analysis of cotinine glucuronide in urine and blood for smoking cessation verification.</li>
<li><strong>Pharmacokinetic Studies</strong>: Researching nicotine metabolism rates and clearance profiles in clinical trials.</li>
<li><strong>Quality Control</strong>: Calibration of LC-MS/MS instruments for environmental and occupational health monitoring.</li>
</ul>
<h3>Precautions</h3>
<ul>
<li>Store at -20°C in dark, airtight containers to prevent hydrolysis.</li>
<li>Handle with PPE; avoid inhalation or skin contact during weighing.</li>
<li>Not for human diagnostic use; restricted to laboratory research applications only.</li>
</ul>