*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Cocarboxylase Tetrahydrate (>90%) is a water-soluble thiamine derivative used as an active pharmaceutical ingredient. It functions as a coenzyme in decarboxylation reactions within the Krebs cycle. The molecular formula is <strong>C12H17ClN4OS·4H2O</strong>, with CAS number <strong>6586-40-3</strong>.</p>
<h3>Application</h3>
<ul>
<li>Vitamin B1 deficiency treatment and metabolic disorders.</li>
<li>Adjunct therapy for diabetic neuropathy and peripheral nerve damage.</li>
<li>Nutritional support in parenteral nutrition formulations.</li>
<li>Industrial synthesis of high-purity thiamine intermediates.</li>
</ul>
<h3>Precautions</h3>
<p>Store below 25°C in dry, sealed containers to prevent hydrolysis. Avoid inhalation of dust; wear appropriate PPE during handling. Contraindicated in patients with known hypersensitivity to thiamine derivatives.</p>