Category:
Veterinary API
CAS NO:
84957-30-2
Standard:
BP,In-house Standards,
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Basic Info
CAS Number
84957-30-2
Pharmacopoeia
BP,In-house Standards
Grade
Veterinary Grade
Is Manufacturer
YES
Samples Provided
NO
Packaging & Delivery
Packaging Specification
1kg/tin
Delivery Cycle
1 Week
Product Description
Specifications
|
Appearance: |
White to pale yellow crystalline powder |
|
Melting point |
>160°C (dec.) |
|
Solubility |
DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
|
Purity (HPLC) |
99% |
|
Storage temp. |
Hygroscopic, -20°C Freezer, Under inert atmosphere |
AI Product Description
*The following content is generated by AI and is for reference only.
CEFQUINOME is a fourth-generation cephalosporin antibiotic characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Its molecular formula is C20H21N5O8S3, and it carries the CAS Registry Number 169428-73-7. This compound features a unique structure that includes a methoxyimino group at position 7 of the beta-lactam ring, significantly enhancing its stability against various beta-lactamases produced by resistant pathogens. As a veterinary drug, Cefquinome is primarily utilized in the treatment of respiratory tract infections, mastitis, skin infections, and systemic bacterial infections in livestock, poultry, and companion animals.
The mechanism of action involves the inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Unlike earlier generations, Cefquinome demonstrates superior penetration into tissues and body fluids, making it highly effective for deep-seated infections. It exhibits strong activity against common veterinary pathogens such as *Escherichia coli*, *Pasteurella multocida*, *Staphylococcus aureus*, and *Streptococcus* species. Notably, its efficacy remains robust even against strains producing extended-spectrum beta-lactamases (ESBLs), which often render other antibiotics ineffective.
In clinical practice, Cefquinome is administered via intramuscular or intravenous injection, ensuring rapid therapeutic blood concentrations. Its pharmacokinetic profile supports once-daily dosing regimens, improving compliance for farmers and veterinarians while reducing stress on the animal. The drug has been approved for use in cattle, pigs, sheep, goats, horses, and chickens in numerous countries globally. However, strict adherence to withdrawal periods is mandatory to prevent residues in meat and milk, ensuring food safety for consumers. Resistance development is monitored closely, and prudent use guidelines are enforced to maintain long-term efficacy. Cefquinome represents a critical tool in modern veterinary medicine, bridging the gap between human-grade antimicrobial standards and animal health needs. Its continued availability helps mitigate economic losses associated with bacterial diseases in agriculture, supporting global food security and sustainable farming practices.
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