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Other Specialized Reagents

BOC-3,5-DIIODO-D-TYROSINE

Category:

Other Specialized Reagents

CAS NO:

214630-08-7

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

214630-08-7

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

BOC-3,5-diiodo-D-tyrosine is a specialized synthetic amino acid derivative widely utilized in the fields of medicinal chemistry and radiopharmaceutical research. Its chemical structure features a tyrosine backbone where the phenolic ring is substituted with two iodine atoms at the 3 and 5 positions, and the alpha-amino group is protected by a tert-butyloxycarbonyl (BOC) moiety. The stereochemistry is defined as D-enantiomeric, distinguishing it from the naturally occurring L-isomer found in proteins. This specific configuration often imparts unique biological properties or metabolic stability required for advanced drug development. The molecular formula of this compound is C14H17I2NO5, corresponding to a high molecular weight due to the presence of two heavy iodine atoms. Its CAS number is 100968-86-1, serving as a critical identifier for inventory management and safety data sheet retrieval. The primary application of BOC-3,5-diiodo-D-tyrosine lies in the synthesis of thyroid hormone analogs and potential anti-cancer agents. Iodinated tyrosine derivatives are fundamental precursors for creating radiolabeled compounds used in diagnostic imaging, particularly in single-photon emission computed tomography (SPECT) or positron emission tomography (PET). The BOC protecting group ensures that the amine functionality remains inert during multi-step organic syntheses, allowing chemists to selectively modify other parts of the molecule before final deprotection. Furthermore, this reagent plays a pivotal role in the study of thyroid metabolism and receptor binding studies. Researchers utilize it to investigate how structural modifications affect the affinity of molecules for thyroid receptors or transport proteins. In pharmaceutical manufacturing, it serves as an intermediate for generating novel therapeutic candidates targeting thyroid disorders or various malignancies. Due to its sensitivity to light and potential reactivity, proper storage under inert atmospheres and protection from UV radiation is essential to maintain purity. Overall, BOC-3,5-diiodo-D-tyrosine represents a vital building block for scientists aiming to advance diagnostics and therapeutics involving halogenated amino acids.