Pharmaceutical intermediates
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Bivalirudin is a <strong>reversible direct thrombin inhibitor</strong> used in interventional cardiology. Its chemical structure is defined by the molecular formula C<sub>62</sub>H<sub>91</sub>N<sub>17</sub>O<sub>18</sub>S<sub>2</sub> and CAS No. 94357-06-3.</p>
<h3>Application</h3>
<ul>
<li><strong>Percutaneous Coronary Intervention (PCI)</strong>: Prevents acute clotting during stent placement.</li>
<li><strong>Unstable Angina Management</strong>: Controls ischemic events in high-risk patients.</li>
<li><strong>Cardiac Surgery</strong>: Serves as an anticoagulant alternative to heparin in bypass procedures.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in severe renal impairment and active major bleeding. Requires storage at controlled room temperature (20°C–25°C) with protection from light and moisture to maintain stability.</p>