UPAZFOMIRKHLDX-UHFFFAOYSA-N;BisoprololImpurity1;BisoprololImpurity23;BisoprololHydroxyethylEsterImpurity;BisoprololImpurity44;2-Hydroxyethyl4-[((2RS)-2-Hydroxy-3-(isoproChemicalbookpylamino)propyl)oxy]benzoate;2-hydroxyethyl4-(2-hydroxy-3-(isopropylamino)propoxy)benzoate;Benzoicacid,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-,2-hydroxyethylester
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<h3>Overview</h3>
<p>Bisoprolol Hydroxyethyl Ester Impurity D is a critical reference standard for quality control in beta-blocker synthesis. It serves as an essential process-related impurity identified during the manufacturing of bisoprolol fumarate. The compound features the <strong>molecular formula C18H30NO4</strong> and is cataloged under <strong>CAS No. 152976-65-3</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical R&D:</strong> Used to validate analytical methods like HPLC and LC-MS for impurity profiling.</li>
<li><strong>Quality Assurance:</strong> Applied in stability testing to monitor degradation pathways during drug storage.</li>
<li><strong>Regulatory Compliance:</strong> Required by FDA and EMA guidelines for establishing acceptable limits in active pharmaceutical ingredients.</li>
</ul>
<h3>Precautions</h3>
<p>Store strictly at -20°C in a dry, inert atmosphere to prevent hydrolysis. Handling requires appropriate PPE including gloves and goggles due to potential irritant properties. Do not use as a therapeutic agent; strictly for laboratory research and development purposes only.</p>