*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Biotin PEG Maleimide is a heterobifunctional crosslinker featuring <strong>biotin</strong>, a <strong>polyethylene glycol (PEG)</strong> spacer, and a <strong>maleimide</strong> group. It facilitates bioconjugation between thiol-containing biomolecules and biotinylated targets via stable thioether bonds. Molecular formula: C<sub>25</sub>H<sub>40</sub>N<sub>4</sub>O<sub>7</sub>S; CAS No.: 126989-34-6.</p>
<h3>Application</h3>
<ul>
<li><strong>Antibody Drug Conjugates (ADCs):</strong> Linking cytotoxic drugs to antibodies for targeted cancer therapy.</li>
<li><strong>In Vitro Diagnostics:</strong> Immobilizing enzymes or antigens on biosensor surfaces for high-sensitivity detection.</li>
<li><strong>Proteomics:</strong> Strengthening protein-biotin interactions in pull-down assays and mass spectrometry workflows.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent hydrolysis. Avoid skin contact and inhalation; use appropriate PPE. Not approved for direct clinical administration as a standalone therapeutic agent.</p>