*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Bedaquiline-d6 is a stable isotopically labeled internal standard used in mass spectrometry for quantitative analysis of the antitubercular drug Bedaquiline. Produced via deuterium exchange or specific synthesis, it serves as a critical reference in pharmacokinetic studies. <strong>Molecular Formula</strong>: C29H24D6F6N4O2S; <strong>CAS No.</strong>: 1587200-00-0 (mixture of diastereomers).</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmacokinetics:</strong> Quantification of Bedaquiline plasma concentrations in clinical trials.</li>
<li><strong>Metabolism Studies:</strong> Tracking metabolic pathways and identifying metabolites in vitro and in vivo.</li>
<li><strong>Quality Control:</strong> Validating assay methods for drug substance and finished product purity.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent degradation. Handle with appropriate PPE; avoid inhalation or skin contact. Not for human use; strictly for analytical research purposes only.</p>