*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Azide PEG Amine, TFA Salt is a heterobifunctional PEG reagent featuring an azido group and a primary amine protected by trifluoroacetic acid. It facilitates bioconjugation via copper-free click chemistry or standard amidation. <strong>Molecular Formula</strong>: C<sub>n</sub>H<sub>2n+1</sub>N<sub>5</sub>O<sub>m</sub>; <strong>CAS No.</strong>: Varies by chain length (e.g., ~100679-48-9 for mPEG).</p>
<h3>Application</h3>
<ul>
<li>Antibody-Drug Conjugates (ADCs) development for targeted delivery.</li>
<li>Peptide modification to enhance pharmacokinetic profiles.</li>
<li>Surface functionalization of nanoparticles for drug loading.</li>
<li>In vivo imaging probe synthesis via strain-promoted azide-alkyne cycloaddition.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent hydrolysis and oxidation. Avoid contact with strong reducing agents which may decompose the azide moiety. Handle in fume hoods due to potential toxicity of residual TFA and explosive risks of concentrated azides.</p>