Azacytidine is an antimetabolic, antitumor drug that is mainly used in adults with high-risk myelodysplastic and myelodysplastic syndromes, and is also used in the treatment of chronic monocytic leukemia and acute myelogenous leukemia
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<h3>Overview</h3>
<p>Azacitidine α-Isomer Impurity is a critical reference standard used to identify and quantify specific degradation products in the manufacturing of <strong>Azacitidine</strong>. This compound arises from stereoisomeric variations during synthesis. Its molecular formula is C<sub>8</sub>H<sub>12</sub>N<sub>4</sub>O<sub>2</sub>, with CAS No. 59067-57-3.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical QC:</strong> Used for method validation and impurity profiling in HPLC systems.</li>
<li><strong>R&D:</strong> Serves as a control material for stability studies of antineoplastic agents.</li>
<li><strong>Regulatory Compliance:</strong> Essential for generating data required by FDA and EMA guidelines.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C in a desiccated environment away from light. Handle only in certified fume hoods due to potential genotoxicity; PPE including gloves and goggles is mandatory during manipulation.</p>