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CAS NO:
154947-66-7
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Antibacterial Protein LL-37 (human)
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Main Sales Markets:
North America,Central/South America,Western Europe,Eastern Europe,
Australasia,Asia,Middle East,Africa
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Hangzhou Go Top Peptide Biotech Co.,Ltd.
2
Years
Basic Info
CAS Number
154947-66-7
Pharmacopoeia
In-house Standards
Grade
Research grade
Is Manufacturer
No
Packaging & Delivery
Packaging Specification
500mg,1g, 10g,50g 100g per package with icebag
Minimum Order Quantity
10mg
Delivery Cycle
In stock or 2-3weeks
Product Description
LL-37 is a multifunctional antimicrobial peptide, which has the potential to be developed into a drug with dual functions of antibacterial and immunity enhancing. LL-37 is the only member of the cathelicidin family, which has been found in human body so far. It is also the only amphiphilic α - helix antibacterial peptide in human body. LL-37 is widely distributed in human blood cells and epithelial cells, and has broad-spectrum antibacterial effect. The antibacterial activity depends on the formation of its spiral conformation, and kills bacteria through the "carpet like" mechanism. LL-37 has the function of neutralizing endotoxin, binding with LPS and CD14, neutralizing the biological activity of LPS, and using formyl peptide receptor like 1 (FPRL1) as receptor-mediated chemotaxis, recruiting immune cells to the infected site and clearing the pathogens. Many infectious diseases are related to low expression or dysfunction of LL-37.
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