The expression of Annexin A1 in different tumor tissues is different, even in the same tumor, the expression of different types is also different. The abnormal expression of Annexin A1 and changes in intracellular localization may be related to the differentiation and metastasis of various malignant tumors. Annexin A1 has a strong relationship with tumors and can be used as a new criterion for early diagnosis, treatment and postoperative tumors. In peptide synthesis, Annexin A1 (1-25) is composed of 25 amino acids coupled with an acetylated structure at the N-terminus.