*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Amine PEG12Amine is a <strong>difunctional polyethylene glycol</strong> derivative featuring terminal amino groups. Synthesized via <strong>nucleophilic substitution</strong>, its core structure enables versatile bioconjugation. Molecular formula: <strong>C<sub>60</sub>H<sub>124</sub>N<sub>2</sub>O<sub>29</sub></strong>; CAS No.: 127589-57-3.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceuticals:</strong> Construction of antibody-drug conjugates (ADCs) and PEGylated protein therapeutics to enhance half-life.</li>
<li><strong>Biomaterials:</strong> Fabrication of hydrogels and drug delivery nanoparticles for controlled release systems.</li>
<li><strong>Diagnostics:</strong> Functionalization of surface probes and fluorescent labeling agents in immunoassays.</li>
</ul>
<h3>Precautions</h3>
<p>Store under <strong>inert atmosphere</strong> at -20°C to prevent oxidation. Avoid direct contact with skin; use appropriate PPE due to potential irritancy. Not intended for direct human injection without further formulation and regulatory approval.</p>