*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Amantadine-d15 Hydrochloride</strong> is a deuterated isotopologue of the antiviral agent amantadine, synthesized via <strong>isotopic exchange</strong> or specific deuteration pathways. Its molecular formula is C<sub>10</sub>H<sub>14</sub>D<sub>15</sub>ClN·HCl with CAS No. 127696-88-0, serving as a high-purity reference standard for mass spectrometry.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmacokinetic Studies:</strong> Utilized as an internal standard in LC-MS/MS assays to quantify endogenous amantadine levels.</li>
<li><strong>Clinical Trials:</strong> Supports bioequivalence testing and metabolic profiling in drug development pipelines.</li>
<li><strong>Quality Control:</strong> Validates analytical methods for detecting trace impurities in bulk pharmaceutical ingredients.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly designated for research use only; not approved for clinical administration. Store under <strong>-20°C</strong> in a desiccated environment to prevent hydrolysis. Handle with appropriate PPE to avoid inhalation or dermal contact during weighing.</p>