*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Acipimox-d4</strong> is a deuterated isotopologue of the antilipemic agent Acipimox, synthesized via selective deuteration for use as an internal standard in quantitative LC-MS/MS assays. Its molecular formula is C7H6D5NO2, with CAS No. 100955-86-4.</p>
<h3>Application</h3>
<ul>
<li><li>Pharmaceutical Analysis: Serves as a stable reference standard for validating bioequivalence studies and pharmacokinetic profiling of Acipimox.</li>
<li><li>Clinical Research: Enables precise quantification of drug metabolites in plasma and urine samples during metabolic pathway investigations.</li>
<li><li>Quality Control: Utilized in manufacturing to monitor impurity profiles and ensure batch consistency in API production.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent isotopic exchange. Handle in a fume hood using appropriate PPE; avoid inhalation or skin contact due to potential irritancy associated with organic acids.</p>