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Other Specialized Reagents

5-Chloro-2-Cyanopyridine

Category:

Other Specialized Reagents

CAS NO:

89809-64-3

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

89809-64-3

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

5-Chloro-2-cyanopyridine is a versatile heterocyclic building block widely utilized in organic synthesis and pharmaceutical research. With the molecular formula C6H3ClN2 and a CAS registry number of 1079-66-9, this compound features a pyridine ring substituted with both a chlorine atom at the fifth position and a cyano group at the second position. The presence of these two functional groups imparts unique reactivity, making it an ideal precursor for constructing complex nitrogen-containing heterocycles. The primary application of 5-chloro-2-cyanopyridine lies in its role as a key intermediate in the development of novel agrochemicals and active pharmaceutical ingredients (APIs). The chlorine substituent allows for facile nucleophilic substitution reactions, enabling chemists to introduce diverse amine, thiol, or alkoxide moieties easily. Simultaneously, the electron-withdrawing nature of the adjacent cyano group activates the ring toward further transformations, facilitating the formation of quinolines, isoquinolines, and other fused heteroaromatic systems. These structural motifs are frequently found in drugs targeting cardiovascular diseases, anti-inflammatory agents, and antimalarial compounds. In the agricultural sector, derivatives synthesized from this starting material serve as effective herbicides, fungicides, and insecticides due to their ability to interact with specific biological enzymes and receptors. Its high stability under standard storage conditions ensures reliability during industrial-scale production processes. Furthermore, researchers value this compound for its solubility characteristics in common organic solvents, which simplifies purification and reaction monitoring. As a critical component in medicinal chemistry libraries, 5-chloro-2-cyanopyridine accelerates the discovery of new therapeutic candidates by providing a robust scaffold for rapid analog generation. Its commercial availability supports continuous innovation across multiple scientific disciplines, driving advancements in drug design and crop protection technologies. Whether used in academic laboratories or large-scale manufacturing facilities, this chemical remains indispensable for creating molecules with significant biological activity and economic value in modern chemical industries.