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Other Specialized Reagents

4-Ethoxy-3-Nitropyridine

Category:

Other Specialized Reagents

CAS NO:

1796-84-5

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

1796-84-5

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

4-Ethoxy-3-nitropyridine is a specialized heterocyclic compound widely recognized in the pharmaceutical and agrochemical industries for its role as a versatile synthetic intermediate. With the chemical formula C7H8N2O3 and the CAS registry number 1006-97-5, this substance features a pyridine ring substituted with an ethoxy group at the fourth position and a nitro group at the third position. The unique electronic distribution created by these substituents makes the molecule highly reactive toward nucleophilic substitution reactions, particularly at the carbon atom adjacent to the nitro group. This reactivity profile allows chemists to efficiently introduce various functional groups, facilitating the construction of complex molecular architectures required for drug development. In practical applications, 4-Ethoxy-3-nitropyridine serves as a critical building block for synthesizing diverse nitrogen-containing heterocycles. It is frequently employed in the production of advanced pharmaceutical agents, including potential anti-inflammatory drugs, antiviral compounds, and kinase inhibitors. The presence of the nitro group offers a convenient pathway for reduction to an amine, which can then be further derivatized into sulfonamides or other biologically active moieties. Similarly, in the agricultural sector, this intermediate contributes to the synthesis of novel pesticides and herbicides designed to enhance crop yield and protect against specific pests. The compound typically appears as a pale yellow to orange crystalline solid, characterized by moderate solubility in organic solvents such as ethanol, methanol, and dichloromethane, while remaining sparingly soluble in water. Its stability under standard storage conditions makes it suitable for industrial-scale manufacturing processes. However, handling requires adherence to safety protocols due to the potential hazards associated with nitro compounds. As research into targeted therapies continues to evolve, 4-Ethoxy-3-nitropyridine remains an indispensable tool for medicinal chemists seeking to optimize lead compounds. Its ability to undergo selective transformations ensures its continued relevance in the discovery pipeline for next-generation therapeutics and agrochemical solutions, bridging the gap between fundamental organic chemistry and applied industrial science.