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Other Specialized Reagents

3,5-Difluoropyridine-2-carboxylic Acid

Category:

Other Specialized Reagents

CAS NO:

745784-04-7

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

745784-04-7

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

3,5-Difluoropyridine-2-carboxylic acid is a specialized heterocyclic compound widely utilized in the fields of medicinal chemistry and agrochemical research. With the chemical formula C6H3F2NO2 and a molecular weight of approximately 157.09 g/mol, this molecule features a pyridine ring substituted with two fluorine atoms at the third and fifth positions and a carboxylic acid group at the second position. Its primary CAS registry number is 1245877-43-9, though specific variations may exist depending on the salt form or purity grade supplied by different manufacturers. The strategic placement of fluorine atoms significantly enhances the metabolic stability and lipophilicity of the resulting derivatives, making this building block highly valuable for pharmaceutical development. In drug discovery, it serves as a crucial intermediate for synthesizing complex kinase inhibitors, anti-inflammatory agents, and antiviral compounds. The electron-withdrawing nature of the fluorine substituents modulates the electronic properties of the pyridine core, influencing binding affinity to biological targets. Furthermore, the carboxylic acid functionality provides a versatile handle for amide bond formation, allowing chemists to attach diverse side chains to create libraries of potential therapeutics. In the agrochemical sector, this compound is employed in the synthesis of novel herbicides and fungicides. The structural motif contributes to improved environmental persistence and targeted efficacy against specific plant pathogens. Researchers leverage its unique reactivity to optimize lead compounds, aiming to reduce toxicity while maximizing therapeutic index. High-purity grades are essential for these applications to ensure reproducibility in clinical trials and field tests. As the demand for precision agriculture and advanced small-molecule drugs grows, 3,5-difluoropyridine-2-carboxylic acid remains an indispensable reagent in modern organic synthesis laboratories. Its availability from various chemical suppliers supports global innovation in creating next-generation active pharmaceutical ingredients and crop protection agents, driving advancements in human health and food security through rational molecular design.