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Other Specialized Reagents

3,5-Dichloro-2-Aminopyridine

Category:

Other Specialized Reagents

CAS NO:

4214-74-8

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

4214-74-8

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

3,5-Dichloro-2-aminopyridine is a vital heterocyclic building block widely utilized in the pharmaceutical and agrochemical industries. With the chemical formula C₅H₄Cl₂N₂ and CAS Registry Number 1084-79-7, this compound features a pyridine ring substituted with two chlorine atoms at the third and fifth positions and an amino group at the second position. Its unique structural configuration endows it with significant reactivity, making it an essential intermediate for synthesizing complex nitrogen-containing molecules. In the pharmaceutical sector, 3,5-dichloro-2-aminopyridine serves as a key precursor for developing novel therapeutic agents, particularly those targeting central nervous system disorders, cardiovascular conditions, and anti-inflammatory pathways. The presence of the electron-withdrawing chloro groups activates the ring towards nucleophilic substitution, while the amino group offers versatile sites for further functionalization. This allows medicinal chemists to construct diverse scaffolds, including kinase inhibitors and antimicrobial drugs, with high efficiency. Similarly, in agriculture, this compound plays a crucial role in the production of modern herbicides and fungicides. Its ability to modulate biological activity through specific receptor interactions makes it valuable for creating crop protection chemicals that are both effective and environmentally considerate. The synthesis process typically involves controlled chlorination of 2-aminopyridine derivatives or condensation reactions involving dichloro precursors, requiring strict adherence to safety protocols due to the potential toxicity of halogenated compounds. From a manufacturing perspective, high-purity grades are preferred to ensure consistent reaction yields and product quality in downstream applications. Researchers often utilize this reagent in multi-step organic syntheses where regioselectivity is paramount. As global demand for advanced active pharmaceutical ingredients (APIs) continues to rise, the strategic importance of 3,5-dichloro-2-aminopyridine in fine chemical supply chains remains robust. Its versatility underscores its status as a cornerstone material for innovation in drug discovery and agricultural science, driving continuous research into new derivatives and optimized synthetic routes.