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Other Specialized Reagents

3,5-Dibromo-2-chloropyridine

Category:

Other Specialized Reagents

CAS NO:

40360-47-2

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

40360-47-2

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

3,5-Dibromo-2-chloropyridine is a versatile heterocyclic intermediate widely utilized in the pharmaceutical and agrochemical industries for the synthesis of complex organic molecules. With the chemical formula C5HBr2ClN and CAS number 100496-87-5, this compound features a pyridine ring substituted with two bromine atoms at the 3 and 5 positions and a chlorine atom at the 2 position. The presence of multiple halogen substituents renders it highly reactive toward nucleophilic substitution and cross-coupling reactions, making it an essential building block for constructing biologically active scaffolds. The primary application of 3,5-dibromo-2-chloropyridine lies in the development of novel drug candidates. Its unique substitution pattern allows chemists to selectively introduce various functional groups through palladium-catalyzed cross-coupling methodologies, such as Suzuki-Miyaura, Stille, or Sonogashira couplings. This selectivity is crucial for synthesizing kinase inhibitors, antitumor agents, and other therapeutic compounds where precise structural modifications are required to optimize biological activity and pharmacokinetic properties. Furthermore, in the agricultural sector, this reagent serves as a key precursor for producing advanced pesticides and herbicides that target specific pests while minimizing environmental impact. From a synthetic chemistry perspective, the compound offers significant advantages due to its stability under standard storage conditions and high purity levels typically available from reputable suppliers. The distinct electronic environment created by the electron-withdrawing halogens facilitates controlled reaction pathways, enabling the efficient construction of diverse molecular architectures. Researchers often employ this intermediate to access fused heterocyclic systems or extended conjugated structures found in advanced materials science applications. As the demand for specialized fine chemicals continues to grow, 3,5-dibromo-2-chloropyridine remains a cornerstone material for innovation in medicinal chemistry and process development. Its ability to undergo multi-step transformations without degradation ensures reliable performance in large-scale manufacturing processes, supporting the global pipeline of new chemical entities entering clinical trials.