3-Pyridine sulphonyl chloride
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<h3>Overview</h3>
<p><strong>3-Pyridinesulfonyl chloride</strong> (CAS 1762-40-5, C<sub>6</sub>H<sub>4</sub>ClNO<sub>2</sub>S) is a key heterocyclic intermediate synthesized via sulfonation of pyridine followed by chlorination. It serves as a vital electrophilic reagent in organic synthesis.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical manufacturing for sulfonylurea antidiabetic agents.</li>
<li>Agrochemical production of pyridine-based herbicides and fungicides.</li>
<li>Material science for synthesizing specialized sulfonamide polymers.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly store in sealed, dry containers under inert atmosphere to prevent hydrolysis. Requires PPE due to corrosive nature; avoid inhalation and skin contact during handling.</p>