Formula Weight: 240.10
Appearance: White or off-white crystal
Purity(HPLC): ≥98.0%
Melting point: 164.0168.0
Single impurity: ≤1.0%
Total impurity: ≤2.0%
Residue: ≤0.2%
Loss on drying: ≤0.2%
Characters: The product is a white or off-white crystal. It's dissolvable slightly in alcohol, benzene, acetone, insolvable in water.
Usage: An intermediate for Benazepril.
Package: 25kgs fibre drum or as request.
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>3-Bromo-1,3,4,5-tetrahydro-2H-1-Benzazepine-2-one</strong> is a specialized heterocyclic intermediate primarily synthesized via bromination of the parent benzazepinone scaffold. It serves as a critical building block in pharmaceutical R&D for constructing complex nitrogen-containing frameworks. <strong>Molecular Formula</strong>: C<sub>9</sub>H<sub>8</sub>BrNO<sub>2</sub>; <strong>CAS No.</strong>: 100678-73-9.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical synthesis: Precursor for central nervous system (CNS) active agents and receptor modulators.</li>
<li>Medicinal chemistry: Used in structure-activity relationship (SAR) studies to optimize drug potency.</li>
<li>Custom manufacturing: Supply for contract development and manufacturing organizations (CDMOs).</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent hydrolysis. Use appropriate PPE including nitrile gloves and safety goggles due to potential irritant properties. Ensure adequate ventilation during handling to avoid inhalation of dust or vapors.</p>