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Other Specialized Reagents

2,5-Dibromo-4-Methylpyridine

Category:

Other Specialized Reagents

CAS NO:

3430-26-0

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

3430-26-0

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

2,5-Dibromo-4-methylpyridine is a specialized heterocyclic organic compound widely utilized in the fields of pharmaceutical research and agrochemical synthesis. With the chemical formula C6H5Br2N and the CAS Registry Number 31978-09-7, this molecule features a pyridine ring substituted with two bromine atoms at the second and fifth positions and a methyl group at the fourth position. This unique substitution pattern endows the compound with high reactivity, making it an invaluable building block for constructing complex nitrogen-containing heterocycles through cross-coupling reactions. The primary application of 2,5-dibromo-4-methylpyridine lies in its role as a versatile intermediate in medicinal chemistry. Researchers frequently employ it to synthesize novel kinase inhibitors, anti-inflammatory agents, and other bioactive molecules. The presence of two distinct halogen sites allows for selective functionalization, enabling chemists to introduce diverse substituents via palladium-catalyzed Suzuki-Miyaura or Stille couplings. This selectivity is crucial for optimizing the pharmacological properties of drug candidates, such as improving metabolic stability or enhancing binding affinity to specific biological targets. Beyond pharmaceuticals, this compound finds significant utility in the development of advanced materials and agrochemicals. It serves as a precursor for synthesizing ligands used in catalysis and components for liquid crystals or organic semiconductors. In agriculture, derivatives based on this scaffold are investigated for their potential as fungicides or herbicides, contributing to crop protection strategies. The methyl group further offers a site for oxidation or reduction, providing additional synthetic flexibility for tailoring molecular structures to specific performance requirements. Due to its sensitivity to light and moisture, proper storage conditions are essential to maintain purity and efficacy. Typically handled under inert atmospheres, this reagent requires careful safety protocols during handling to prevent exposure. As the demand for sophisticated heterocyclic scaffolds grows in both academic and industrial laboratories, 2,5-dibromo-4-methylpyridine remains a critical tool for advancing chemical innovation. Its ability to facilitate the rapid assembly of complex architectures underscores its importance in modern synthetic methodology, supporting the continuous discovery of new therapeutic agents and functional materials across various scientific disciplines.