Category:
Chiral Intermediates
CAS NO:
72235-52-0
Standard:
ChP,
it is the intermediate of DOLUTEGRAVIR.Dolutegravir (GSK1349572) is a HIV integrase inhibitor with an IC50 of 2.7 nM and is moderately effective against the significant mutants Y143R, Q148K, N155H, and G140S/Q148H against Raltegravir.
| 2,4-Difluorobenzylamine Chemical Properties |
| Boiling point | 82-84 °C (15 mmHg) |
| density | 1.204 g/mL at 25 °C(lit.) |
| refractive index | n20/D 1.49(lit.) |
| Fp | 155 °F |
| form | Liquid |
| color | Clear colorless to light yellow |