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Other Specialized Reagents

2-Methoxy-5-Trifluoromethylpyridine

Category:

Other Specialized Reagents

CAS NO:

175277-45-9

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

175277-45-9

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

2-Methoxy-5-trifluoromethylpyridine is a specialized heterocyclic organic compound widely utilized in the pharmaceutical and agrochemical industries as a critical intermediate for the synthesis of complex bioactive molecules. With the molecular formula C7H6F3NO, this substance features a pyridine ring substituted with a methoxy group at the second position and a trifluoromethyl group at the fifth position. The presence of the electron-withdrawing trifluoromethyl moiety significantly enhances the metabolic stability and lipophilicity of the resulting derivatives, making it an invaluable building block for medicinal chemists aiming to optimize drug candidates. The primary application of 2-methoxy-5-trifluoromethylpyridine lies in its role as a precursor for various nitrogen-containing heterocycles found in modern therapeutics. It serves as a key scaffold in the development of kinase inhibitors, antiviral agents, and antifungal compounds. In the agricultural sector, this compound contributes to the synthesis of novel herbicides and fungicides that offer improved efficacy and environmental profiles compared to older generations of chemicals. Its unique chemical structure allows for versatile functionalization through standard cross-coupling reactions, nucleophilic substitutions, and reduction processes, providing synthetic flexibility essential for rapid lead optimization in drug discovery pipelines. Safety data indicates that while generally stable under standard storage conditions, this compound should be handled with appropriate personal protective equipment due to potential irritation risks associated with fluorinated aromatics. Proper ventilation and containment are recommended during handling to prevent inhalation or skin contact. The compound is typically supplied as a high-purity liquid or crystalline solid, depending on the specific grade required by the customer. As global demand for innovative crop protection solutions and advanced pharmaceuticals continues to rise, the strategic importance of such fluorinated pyridine derivatives remains paramount in the fine chemical manufacturing landscape. Researchers and industrial chemists rely on its consistent quality and reactivity to accelerate the timeline from initial design to clinical or commercial deployment, ensuring that next-generation products meet rigorous regulatory standards while delivering superior therapeutic or agronomic performance.