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Other Specialized Reagents

2-Fluoro-3-Trifluoromethylpyridine

Category:

Other Specialized Reagents

CAS NO:

65753-52-8

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

65753-52-8

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

2-Fluoro-3-trifluoromethylpyridine is a specialized heterocyclic organic compound widely recognized in medicinal chemistry and agrochemical research. With the molecular formula C6H3F4N, this molecule features a pyridine ring substituted with a fluorine atom at the second position and a trifluoromethyl group at the third position. Its primary CAS registry number is 1879-05-0, ensuring precise identification for regulatory compliance and inventory management across global laboratories. The unique electronic properties of 2-fluoro-3-trifluoromethylpyridine make it an invaluable building block for synthesizing complex bioactive molecules. The presence of the highly electronegative fluorine atoms significantly alters the lipophilicity and metabolic stability of target compounds. Consequently, pharmaceutical researchers frequently utilize this reagent as a key intermediate in the development of novel kinase inhibitors, antiviral agents, and antifungal drugs. The trifluoromethyl group, known for enhancing membrane permeability and binding affinity, combined with the reactive fluoro substituent, allows for efficient nucleophilic aromatic substitution reactions. This facilitates the introduction of diverse functional groups required to fine-tune drug efficacy and pharmacokinetic profiles. Beyond the pharmaceutical sector, this compound plays a critical role in the agrochemical industry. It serves as a precursor for synthesizing advanced herbicides and insecticides that offer high potency with reduced environmental persistence. The structural motif found in this molecule often correlates with improved biological activity against specific pest species while maintaining safety for non-target organisms. Furthermore, its stability under various reaction conditions makes it suitable for large-scale manufacturing processes used in industrial chemical production. In laboratory settings, 2-fluoro-3-trifluoromethylpyridine is typically handled as a colorless to pale yellow liquid or solid, depending on purity and temperature. Proper storage in cool, dry environments away from strong oxidizers is recommended to maintain integrity. Researchers must adhere to standard safety protocols when handling fluorinated compounds due to potential toxicity and corrosive nature. As demand for targeted therapies and sustainable agricultural solutions grows, the strategic application of this versatile pyridine derivative continues to expand, driving innovation in drug discovery and crop protection technologies worldwide.