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Other Specialized Reagents

2-Amino-5-Chloropyridine

Category:

Other Specialized Reagents

CAS NO:

1072-98-6

Standard:

BP,USP,

Price Range:

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Main Sales Markets:

North America,Western Europe,Eastern Europe

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Shanghai Sunwise Chemical Co., Ltd.

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Basic Info

CAS Number

1072-98-6

Pharmacopoeia

BP,USP

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Pharmaceutical Raw Materials and Intermediates

AI Product Description

*The following content is generated by AI and is for reference only.

2-Amino-5-chloropyridine is a vital heterocyclic intermediate widely utilized in the pharmaceutical and agrochemical industries. With the chemical formula C5H5ClN2 and a molecular weight of approximately 128.56 g/mol, this compound features a pyridine ring substituted with an amino group at the second position and a chlorine atom at the fifth position. Its unique structural configuration imparts distinct reactivity, making it an essential building block for synthesizing complex nitrogen-containing heterocycles. The Compound Identification Number (CAS) for 2-Amino-5-chloropyridine is 1947-03-9. In the pharmaceutical sector, this molecule serves as a key precursor for developing various therapeutic agents. It is frequently employed in the synthesis of kinase inhibitors, anti-inflammatory drugs, and antimalarial compounds. The presence of the amino group facilitates nucleophilic substitution reactions, while the chlorine atom allows for further functionalization through palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings. These synthetic pathways enable medicinal chemists to construct diverse molecular scaffolds with high efficiency and selectivity. Beyond medicine, 2-Amino-5-chloropyridine finds significant application in the production of agrochemicals. It acts as a fundamental component in the creation of herbicides and fungicides designed to protect crops from pests and diseases. The stability of the pyridine ring under various environmental conditions ensures that derivatives synthesized from this intermediate retain their biological activity over extended periods. Furthermore, its utility extends to materials science, where it contributes to the development of specialized polymers and luminescent materials. The compound typically appears as a white to off-white crystalline powder or solid. While effective in synthesis, handling requires standard safety precautions due to potential skin irritation and toxicity if ingested or inhaled. Proper storage in cool, dry environments away from incompatible oxidizers is recommended to maintain purity and prevent degradation. As global demand for advanced therapeutic molecules grows, the role of 2-Amino-5-chloropyridine as a versatile synthetic tool remains indispensable for researchers aiming to innovate in drug discovery and agricultural chemistry. Its availability from major chemical suppliers ensures consistent supply chains for industrial applications worldwide.