*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>18-Oxocortisol</strong> is a minor adrenal steroid hormone, chemically defined as 18-oxo-cortisol. Its molecular formula is C<sub>21</sub>H<sub>28</sub>O<sub>6</sub> and CAS No. is 478-92-8. The compound is typically synthesized via semi-synthesis from natural precursors or extracted from plant sources using advanced chromatography techniques.</p>
<h3>Application</h3>
<ul>
<li><strong>Endocrinology Research:</strong> Used as a reference standard for diagnosing mineralocorticoid excess and hypertension.</li>
<li><strong>Biochemical Assays:</strong> Serves as an internal control in mass spectrometry profiling of adrenal steroids.</li>
<li><strong>Pharmaceutical Development:</strong> Investigated for potential therapeutic roles in regulating sodium balance.</li>
</ul>
<h3>Precautions</h3>
<ul>
<li><strong>Storage:</strong> Keep in tightly sealed containers at -20°C protected from light to prevent oxidation.</li>
<li><strong>Safety:</strong> Handle with appropriate PPE; avoid inhalation or skin contact during industrial processing.</li>
<li><strong>Regulatory:</strong> Strictly for research use only; not approved for direct clinical administration without further trials.</li>
</ul>