*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>17Alpha-Des-(2-hydroxyacetyl)budesonide 17Alpha-Carboxylic Acid</strong> is a specific metabolite of the corticosteroid budesonide, primarily utilized in pharmacokinetic studies and impurity profiling. Its molecular formula is C<sub>25</sub>H<sub>32</sub>O<sub>6</sub>, with CAS No. <strong>108093-43-0</strong>. This compound is synthesized via oxidative degradation pathways during drug development to assess metabolic stability.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Analysis:</strong> Serves as a reference standard for quantifying budesonide metabolites in biological fluids.</li>
<li><strong>Quality Control:</strong> Used to validate HPLC methods for detecting trace impurities in finished dosage forms.</li>
<li><strong>Research & Development:</strong> Supports metabolic pathway elucidation and structure-activity relationship (SAR) investigations.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly for research use only; not approved for clinical administration. Store under inert atmosphere at -20°C to prevent hydrolysis. Handle with appropriate PPE due to potential hormonal activity and dust inhalation risks.</p>