*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>10,11-Dihydro-10-hydroxy Carbamazepine-D4 (Major)</strong> is a deuterated metabolite reference standard derived from the antiepileptic drug carbamazepine. Synthesized via selective deuteration to enhance mass spectrometry stability, its molecular formula is C15H10D4N2O2 with CAS 176986-59-9.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmacokinetics:</strong> Used as an internal standard for quantitative LC-MS/MS analysis of carbamazepine metabolism in plasma and urine.</li>
<li><strong>Clinical Research:</strong> Supports bioequivalence studies and therapeutic drug monitoring (TDM) protocols.</li>
<li><strong>Quality Control:</strong> Validates analytical methods in pharmaceutical manufacturing environments.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent degradation. Handle only in certified laboratories using appropriate PPE due to potential toxicity. Not intended for human or veterinary clinical use.</p>