Category:
Vitamin
CAS NO:
523-39-7
Standard:
ChP,USP,BP,EP,JP,In-house Standards,IP,Ph. Int,
![6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one](https://eimg.pharmasources.com/image/20250617/4zoOybJjzUTk0UgguabMkX7VnrDIlxHluERwqkjK.jpg)
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Basic Info
CAS Number
523-39-7
Pharmacopoeia
ChP,USP,BP,EP,JP,In-house Standards,IP,Ph. Int
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Samples Provided
NO
Product Description
Vitamin K2 (45) plays a wide and far-reaching role in the health of various systems of the human body. Appropriate supplementation can enhance physical fitness and prevent a variety of diseases, especially for the bone and cardiovascular system.
AI Product Description
*The following content is generated by AI and is for reference only.
Vitamin K2 MK-9, chemically known as menaquinone-9, is a vital form of Vitamin K characterized by a side chain containing nine isoprene units. Its molecular formula is C45H60O2, and it carries the CAS registry number 3718-62-7. This lipophilic compound belongs to the menaquinone family, distinguished from other forms like MK-4 or MK-7 by its specific length of the hydrophobic tail. Naturally occurring in fermented foods such as natto and certain cheeses, as well as synthesized in the gut microbiota of humans and animals, MK-9 plays an indispensable role in calcium metabolism and cardiovascular health.
The primary biological function of Vitamin K2 MK-9 involves acting as an essential cofactor for the enzyme gamma-glutamyl carboxylase. This enzymatic process activates specific proteins, most notably osteocalcin and matrix Gla protein (MGP). When activated, osteocalcin facilitates the binding of calcium to the bone matrix, thereby enhancing bone mineral density and reducing fracture risk. Simultaneously, MGP prevents calcium deposition in soft tissues, particularly within arterial walls. Consequently, adequate intake of MK-9 is strongly associated with improved vascular elasticity and a reduced likelihood of arterial calcification, a key factor in preventing cardiovascular diseases.
Unlike Vitamin K1, which primarily supports blood coagulation, MK-9 exhibits superior bioavailability and longer half-life in human circulation compared to some shorter-chain variants, allowing for sustained physiological effects. It is widely utilized in dietary supplements targeting bone strength, heart health, and metabolic regulation. While generally recognized as safe, individuals on anticoagulant therapy, such as warfarin, must exercise caution due to potential interactions affecting clotting mechanisms. Research continues to explore its efficacy in managing conditions related to dysregulated calcium distribution, highlighting its significance as a critical micronutrient for long-term systemic wellness.
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