Valacyclovir hydrochloride USP 97%min Pharmaceutical API Anti hepatitis Disease resistant poison made in china 124832-27-5
AI Product Description
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Valacyclovir hydrochloride, a high-purity pharmaceutical active ingredient meeting USP specifications with a minimum potency of 97%, serves as the L-valyl ester prodrug of acyclovir. Its chemical formula is C13H22N6O4·HCl, and it is identified by the CAS number 124832-28-6. This compound is primarily utilized in the treatment of viral infections caused by herpes simplex virus (HSV) types 1 and 2, as well as varicella-zoster virus (VZV). Upon oral administration, Valacyclovir undergoes rapid and extensive first-pass metabolism in the liver and intestine to release acyclovir and valine. Acyclovir then enters infected cells where it is phosphorylated by viral thymidine kinase into its active triphosphate form. This active metabolite competitively inhibits viral DNA polymerase and incorporates into the growing viral DNA chain, causing premature termination of replication.
While often associated with antiviral therapy for conditions like genital herpes, cold sores, and shingles, the specific phrasing "Anti hepatitis Disease" in some product descriptions may be misleading or refer to off-label research contexts, as Valacyclovir is not a standard first-line treatment for hepatitis B or C, which are typically managed with nucleoside analogs like entecavir or interferons. Similarly, terms such as "resistant poison mad" appear to be non-standard descriptors, likely resulting from translation errors or marketing exaggerations rather than clinical terminology. The drug is particularly valuable due to its superior bioavailability compared to acyclovir, allowing for less frequent dosing regimens that improve patient compliance. It is widely prescribed globally for suppressive therapy to reduce transmission risks and outbreak frequency. Pharmaceutical manufacturers ensure strict adherence to United States Pharmacopeia standards to guarantee safety and efficacy for patients suffering from herpesvirus-related ailments.