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<h3>Overview</h3>
<p><strong>Trimethoprim</strong> (CAS: 738-70-5) is a synthetic antibacterial agent with the molecular formula C14H18N4O3. It acts as a dihydrofolate reductase inhibitor, typically produced via chemical synthesis involving condensation of anisidine derivatives.</p>
<h3>Application</h3>
<ul>
<li>Treatment of urinary tract infections in combination with sulfamethoxazole.</li>
<li>Management of respiratory tract infections and otitis media.</li>
<li>Prophylaxis against opportunistic infections in immunocompromised patients.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in pregnancy due to teratogenic risks. Requires storage in cool, dry conditions away from light. Strict adherence to dosage limits is necessary to prevent hematological toxicity.</p>