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<h3>Overview</h3>
<p><strong>Hydroxypropyl-beta-cyclodextrin</strong> (HP-β-CD, CAS 94035-02-6) is a chemically modified cyclodextrin derivative produced via etherification of beta-cyclodextrin with propylene oxide. This water-soluble polymer features the molecular formula C<sub>42</sub>H<sub>70</sub>O<sub>35</sub>(CH<sub>3</sub>)<sub>n</sub>. It serves as a critical solubilizing agent in pharmaceutical manufacturing.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceuticals: Enhances bioavailability of poorly soluble drugs like NSAIDs and antifungals.</li>
<li>Food Industry: Stabilizes flavors and masks bitter tastes in functional beverages.</li>
<li>Cosmetics: Improves delivery of active ingredients in topical formulations.</li>
</ul>
<h3>Precautions</h3>
<p>Store in cool, dry places away from direct sunlight. While generally recognized as safe (GRAS), high intravenous doses require clinical monitoring for renal accumulation. Ensure proper PPE during handling to avoid inhalation of dust particles.</p>