Category:
Vitamin
CAS NO:
59-43-8
Standard:
USP,BP,EP,
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Basic Info
CAS Number
59-43-8
Pharmacopoeia
USP,BP,EP
Grade
Pharmaceutical Grade
Is Manufacturer
No
Samples Provided
NO
Product Description
Usage
：1.To promote growth.
2.To help digestion, especially carbohydrate digestion.
3.To improve mental health, to maintain normal neural tissue, muscle, heart activity.
4.To reduce airsick, seasick.
5.To ease the pain after dental surgery.
6.To elps in the treatment of herpes zoster.
AI Product Description
*The following content is generated by AI and is for reference only.
Thiamine, universally recognized as Vitamin B1, is a water-soluble vitamin essential for human health and metabolic function. Its chemical identity is defined by the molecular formula C12H17ClN4OS5 and the CAS Registry Number 67-03-8. Structurally, thiamine consists of a pyrimidine ring linked to a thiazole ring via a methylene bridge, with a hydroxyethyl group attached to the nitrogen atom of the pyrimidine ring. This unique structure allows it to be converted into its active coenzyme form, thiamine pyrophosphate (TPP), which serves as a critical cofactor in various enzymatic reactions within the body.
The primary biological role of thiamine revolves around energy metabolism. It acts as an indispensable catalyst in the decarboxylation of alpha-keto acids, such as pyruvate and alpha-ketoglutarate, linking glycolysis to the citric acid cycle (Krebs cycle). Without adequate thiamine, cells cannot efficiently convert carbohydrates into adenosine triphosphate (ATP), leading to cellular energy failure. Furthermore, thiamine is vital for nerve function, as it supports the synthesis of neurotransmitters and maintains the integrity of myelin sheaths. Deficiency in this vitamin results in beriberi, a condition characterized by neurological symptoms like peripheral neuropathy and muscle weakness, or cardiovascular issues known as wet beriberi, which can lead to heart failure. In infants, severe deficiency causes infantile beriberi, while chronic alcoholism often precipitates Wernicke-Korsakoff syndrome due to impaired absorption and storage.
Industrially, thiamine is widely utilized in pharmaceutical formulations to treat deficiencies and support nervous system health. It is also a common additive in animal feed to prevent growth retardation and metabolic disorders in livestock and poultry. In the food industry, it is frequently fortified into cereals, flours, and beverages to ensure public nutritional adequacy. Given its stability in acidic conditions but susceptibility to degradation by heat and alkaline environments, proper handling and storage are crucial during manufacturing processes. As an essential nutrient that the human body cannot synthesize de novo, daily dietary intake through whole grains, legumes, pork, and nuts is necessary to maintain optimal physiological performance and prevent debilitating diseases associated with its absence.
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