*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Teriflunomide is an active metabolite of leflunomide, serving as a <strong>immunomodulatory agent</strong>. It functions by inhibiting dihydroorotate dehydrogenase to block pyrimidine synthesis. The molecular formula is C12H9F3N2O2 with CAS number 149656-78-8.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Active Pharmaceutical Ingredient (API) for treating relapsing forms of multiple sclerosis.</li>
<li><strong>Research & Development:</strong> Used in immunology studies to evaluate T-cell proliferation inhibition mechanisms.</li>
<li><strong>Contract Manufacturing:</strong> Bulk supply for generic drug formulations targeting autoimmune disorders.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in pregnancy due to teratogenic risks; requires strict contraception protocols. Store in a cool, dry place below 25°C away from light. Handle with appropriate PPE to avoid inhalation or skin contact during industrial processing.</p>