*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Tenofovir Disoproxil Fumarate is a prodrug of tenofovir, synthesized via esterification to enhance oral bioavailability. Its molecular formula is <strong>C19H26N5O4P</strong> and CAS number is <strong>147127-20-8</strong>.</p>
<h3>Application</h3>
<ul>
<li>HIV-1 treatment in combination antiretroviral therapy regimens.</li>
<li>Chronic Hepatitis B virus (HBV) infection management.</li>
<li>Pre-exposure prophylaxis (PrEP) for high-risk populations.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in severe renal impairment; requires dose adjustment based on creatinine clearance. Store in sealed containers below 25°C with controlled humidity to prevent hydrolysis. Handle with PPE to avoid dermal exposure.</p>