*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Telmisartan combined with <strong>HCTZ</strong> (Hydrochlorothiazide) is a fixed-dose combination API used for hypertension management. The core process involves co-crystallization or physical blending of the ARB and diuretic. Molecular formula: C<sub>33</sub>H<sub>30</sub>N<sub>4</sub>O<sub>6</sub>. CAS No.: 144701-48-4.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Production of oral tablets for uncontrolled hypertension.</li>
<li><strong>Clinical Therapy:</strong> Adjunct treatment when monotherapy is insufficient.</li>
<li><strong>Global Supply Chain:</strong> Bulk sourcing for generic drug formulation.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in pregnancy, severe renal impairment, and anuria. Store in dry conditions below 25°C. Handle with PPE to avoid inhalation of fine powders.</p>