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CAS NO:
17388-39-5
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Basic Info
CAS Number
17388-39-5
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Swertiamarin is a naturally occurring iridoid glycoside primarily isolated from the roots of Gentiana species, particularly Gentiana scabra and Gentiana macrophylla. Its molecular formula is C16H20O9, and it carries the CAS Registry Number 574-83-2. As a key bioactive constituent, swertiamarin contributes significantly to the characteristic bitter taste of these medicinal plants, serving as a natural marker for quality control in traditional herbal preparations.
Pharmacologically, swertiamarin exhibits a broad spectrum of therapeutic potential supported by extensive scientific research. It demonstrates potent hepatoprotective effects, safeguarding liver cells against toxicity induced by various chemical agents such as carbon tetrachloride or alcohol. This protective mechanism is often attributed to its ability to modulate oxidative stress pathways and enhance antioxidant enzyme activity within hepatic tissues. Furthermore, emerging studies suggest promising anti-inflammatory properties, where swertiamarin inhibits pro-inflammatory cytokines, making it a candidate for managing inflammatory conditions.
Beyond liver health, recent investigations have highlighted its potential neuroprotective capabilities. By mitigating neuronal damage and reducing excitotoxicity, this compound shows promise in the context of neurodegenerative disorders. Additionally, swertiamarin possesses notable antidiabetic characteristics, helping to regulate blood glucose levels and improve insulin sensitivity in preclinical models. These diverse biological activities position swertiamarin as a valuable resource in both pharmaceutical development and functional food industries.
In commercial applications, swertiamarin is utilized as a standard reference material for analytical chemistry to ensure the authenticity and potency of Gentiana-based supplements and traditional medicines. It is also explored as a lead compound for synthesizing novel drug candidates targeting metabolic and neurological diseases. While generally considered safe due to its natural origin, ongoing clinical trials are essential to fully establish its efficacy and safety profile for human consumption. The compound represents a fascinating intersection of traditional medicine and modern pharmacology, offering hope for new treatments derived from ancient botanical wisdom. Its unique structure and multifaceted biological actions continue to attract significant attention from researchers worldwide seeking innovative solutions for chronic health challenges.
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