Category:
Prophylactic Biological Products
CAS NO:
1190307-88-0
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APIs for Hormones and Regulatory Drugs
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Sterilizing Equipment
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Filter Paper
Release Modifiers
Immunomodulatory Formulations
Filter Paper Board
smotic Pressure Regulators / Tonicity Adjusting Agents
Water, Electrolyte, and Acid-Base Balance Regulating Formulations
Ph Control Agents
Nozzle, Tank Cleaning Machine
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Antioxidants / Antioxidant Synergists
Fluid Equipment
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Complexing Agents (Chelating Agents / Inclusion Compounds)
Hormonal Formulations
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Co-solvents
ENT Preparations
Penetration Enhancers (Transdermal)
Freeze-drying Protective Agents
Refrigerants / Cryogens
Capsule
Fragrances
Adsorbents
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Stiffening Agents
Carriers for Dry Powder Inhalers (DPI Carriers)
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Pipes and Pipe Fittings
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Compressor
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Prefillable Syringes
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Sanitary Pressure Vessel
Hyaluronic Acid
Collagen
Botulinum Toxin
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Ceramide
Ectoin
Niacinamide
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Chitosan
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Ointment Filling-sealing Machine、Vacuum Mixer
Eye Drug Machinery
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Glass bottles & Vials
Fermentation Products
Prophylactic Biological Products
Mixing Tank/Blender
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Recombinant Collagen
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Veterinary API
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Peptides
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Immunology Reagents
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Syrup Machinery
Injection Medicine Machinery
Hard Capsule Filling Machine
Coating Machine
Medicine Material Grinding Machine
Lettering machine
Box Packaging Machine
Mass Spectrometry
Laboratory Bench
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Chemical Reagents
Cleaning & Disinfection Equipment
Granulator
Emulsifier
Biological Fermentation System
Injection Molding Equipment
Exosome
Phospholipids
Prostaglandins
Veterinary Biologics
Chemical Reagents
Therapeutic Biological Products
Biochemical Reagents
Antibodies
Natural Pigments
Animal Lipids
Enzyme Preparations
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Online Particle Size Analyzer
Tetracycline
Amino Acids and Derivatives
Process Optimization and Testing
Nucleic Acids and Derivatives
Pre-Clinical Research
Chemical/Biological API Manufacturing
Powder Filling Machine
Oral Liquid Machinery
Low Temperature Pulverizer
Strapping machine
Paper Film Packaging Machine
Thermal Analyzers
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Storage Cabinets
Plastic Bottles
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Certification
Feed Additives
Diagnostic Biological Products
Pulverizer
Coating Machine
Capsule Filling Machine
Other Mixing Equipment
Cell Engineering Equipment
Pre-filled Syringe Production Equipment
Purification Equipment
Electrophoresis/Gel Imaging/UV Detection
Regenerative Materials
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Soft Mist Inhaler
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Clinical Trials
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Suppository Drug Machinery
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Printing Device
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Environmental Test Chambers
Moisture Analyzer
Air Discharge Equipment
Rubber Stopper
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Nebulizer
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Proteins
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Medicine Film Drug Machinery
Infusion Medicine Machinery（中文站有输液剂机械的三级分类）
Pharmaceutical Machine Milling
Instruction Booklet Folding Machine
Fan
Chromatography Consumables and Accessories
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Gasket
Sample Preparation / Digestion Equipment
X-ray Structure Analysis
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Counting Machine (Tablet)
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Disposable Biotechnology Equipment
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Laboratory Low-temperature Storage
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Aerosol Drug Machinery
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Trays
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Counting Machine
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Bee Products
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Medicine Filling Machine
Disk Type Bottle Straightening Machine
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Ultrafiltration/Microfiltration System
Horizontal Pillow Packaging Machine
Cartoning Machine
Auto-injector
Transfection/Cell Fusion
Track & Trace
Gas Generators / Gas Handling Equipment
Blood Products
TCM Ingredients & Slices
Animal Medicinal Materials
Lincomycin
Microbial Products
Bottle Washer
Vial Sealing Machine
Liquid Handling Equipment
Hoses and Fittings
Other Biopharmaceutical Equipment
Vertical Packaging Machine
Casing Machine
Microplate Reader/Enzyme Labeling Instrument
Analysis and Validation
Serialization System
Pen Injector
Other Anti-Infective Drug
Other Pharmaceutical R&D Outsourcing
Conveyer For Medicine Material
Spray Pump
Other Injectable Equipment
Aluminum Foil Packaging Machine
Coding Machine
Cell Analysis
Automated Assembly
Other Laboratory General Equipment
Packaging Bag Valve
Freeze Dryer
Granule packaging machine
Other Drug Delivery Device Accessories
Biological Microscope/In Vivo Imaging
Other Antibiotics
Cap Screwing Machine
Nasal Drug Delivery Devices / Nasal Spray Pumps
Printing Services
Liquid Packaging Machine
Laboratory Automation
Screw Capping Machine
Lamp Inspection Machine
Ophthalmic Drug Delivery Devices / Eye Drop Delivery Systems
Labelling
Powder Packaging Machine
Synthesizer
Heat Shrink Packaging Machine
Metal Detector
Insulin Pens / Blood Glucose Management Devices
Security Taggants & Markings
Filter Cartridge
Tablet Packaging Machine
Animal Experiment Instrument
Injection & blow molding machines
Batching system
Self-Injection Systems / Safety Protection Devices
Incubator Equipment
Printed Drugs Packaging
Box filling & sealing machine
Palletizing equipment
CIP cleaning system
Topical / Gynecological / Intimate Drug Delivery Devices
Desiccants
Other Life Science Instrument
Bottle Filling Line
Contaners
Lifting Charging Machine
Others
Inhalant Packaging
BFS Bottlepack Machine
Weighting Equipment
Blister Packaging Machine
Pharmaceutical Paper
Other Pharmaceutical Outer Packaging Equipment
Packaging bag valve
Container Sealing Machine
Glass Tube
Multi-functional Bottle Packaging Machine
Medical Aesthetic Freeze-Dried Powder Vials
Sachets Cartoner Packing line
Primary Packaging
Other Pharmaceutical Inner Packaging Equipment
Aluminum Caps & Aluminum-Plastic Combination Caps
Sterile Bags / Breathing Bags / Sterilization Bags
Medical Device Packaging / Bioconsumables Packaging
Dispensing Bottles
Blister Packaging
Pharmaceutical Plastic Films / Composite Film Bags
Accessories
Ampuls
Other Packaging Materials
Basic Info
CAS Number
1190307-88-0
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
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AI Product Description
*The following content is generated by AI and is for reference only.
Sofosbuvir, marketed under the brand name Sovaldi, is a pioneering nucleotide analog prodrug developed by Gilead Sciences for the treatment of chronic hepatitis C virus (HCV) infection. With the Chemical Abstracts Service (CAS) registry number 850164-23-9, this compound represents a significant milestone in antiviral therapy due to its high efficacy and favorable safety profile. The molecular formula of Sofosbuvir is C22H29FN6O9P, reflecting its complex structure designed to mimic natural nucleotides within the viral replication machinery.
The primary mechanism of action involves the intracellular conversion of Sofosbuvir into its active triphosphate metabolite. This active form competitively inhibits the HCV RNA-dependent RNA polymerase, specifically the NS5B protein, thereby halting viral RNA synthesis and preventing the virus from replicating. Unlike older interferon-based regimens, Sofosbuvir targets the virus directly without requiring immune modulation, making it suitable for patients with compromised liver function or those who have failed previous treatments. It is typically administered as a single daily oral tablet, often in combination with other direct-acting antivirals such as ledipasvir, velpatasvir, or ribavirin, depending on the specific HCV genotype and patient history.
Clinical trials have demonstrated cure rates exceeding 95% across various genotypes, including difficult-to-treat strains like genotype 3. Its approval marked a paradigm shift in hepatology, moving away from lengthy, side-effect-heavy therapies toward short, well-tolerated courses lasting eight to twelve weeks. While generally well-tolerated, common side effects may include fatigue, headache, and nausea. As a cornerstone of modern HCV management, Sofosbuvir has played a crucial role in global efforts to eliminate hepatitis C as a public health threat, significantly reducing transmission rates and associated complications like cirrhosis and hepatocellular carcinoma. Its introduction has set new standards for drug development in the field of antiviral pharmacology, emphasizing precision targeting and patient-centric outcomes.
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Copyright 2006-2025 (All Rights Reserved)
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