Product Description
Serotonin O-Sulfate
Type:Herbal Extract
Variety:Griffonia seed extract
Character:Powder
Extraction method:Solvent Extraction
Packing : Drum,Vacuum Packed
Grade : medicine grade
Molecular Weight : 274.294
molecular formula : 16310-20-6
Appearance : white-like Solid
Product Usage:
medicine intermediate
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Trading manager : Helen Tan
Whatsapp : +86 13930229229
Website: www.blrhbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
Serotonin O-Sulfate, identified by the CAS number 16310-20-6, is a biologically significant metabolite derived from the neurotransmitter serotonin. Chemically known as 5-hydroxytryptamine O-sulfate or 5-hydroxyindole-3-ethylsulfonic acid, its molecular formula is C10H12N2O4S. This compound represents a key pathway in the metabolic breakdown of serotonin within the human body, serving as an intermediate before further degradation into indoleacetic acid and subsequent excretion via urine. Structurally, it consists of an indole ring substituted with a hydroxyl group at the fifth position and an ethylamine side chain, where the hydroxyl moiety has been esterified with sulfuric acid to form a sulfate ester.
In the realm of scientific research, Serotonin O-Sulfate is primarily utilized as a reference standard for analytical chemistry and clinical diagnostics. It plays a crucial role in high-performance liquid chromatography (HPLC) and mass spectrometry studies aimed at quantifying serotonin levels and their metabolic derivatives in biological fluids such as plasma, urine, and cerebrospinal fluid. By analyzing the concentration ratios of serotonin to its sulfated forms, researchers can gain deeper insights into serotonergic system function, which is intimately linked to mood regulation, sleep cycles, appetite control, and gastrointestinal motility. Abnormalities in these metabolic pathways are often investigated in the context of psychiatric disorders, including depression and anxiety, as well as certain carcinoid syndromes.
Furthermore, this compound aids in validating enzymatic assays involving sulfotransferases, enzymes responsible for adding sulfate groups to various endogenous and exogenous substrates. Understanding the kinetics and specificity of these enzymes helps elucidate detoxification mechanisms and drug metabolism processes. While not used directly as a therapeutic agent itself, Serotonin O-Sulfate remains an indispensable tool in pharmaceutical development and neurobiological research. Its study contributes significantly to mapping the complex biochemical networks that govern central nervous system activity, offering potential avenues for developing novel treatments targeting serotonin-related dysfunctions. As a stable and well-characterized metabolite, it continues to support advancements in understanding the intricate balance of neurotransmitters essential for maintaining physiological homeostasis.