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Natural Extracts
CAS NO:
114-49-8
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Basic Info
CAS Number
114-49-8
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Scopolamine hydrobromide is a tropane alkaloid derivative widely utilized in both medical and research contexts. With the chemical formula C17H21NO4·HBr and CAS Registry Number 6533-03-3, this compound serves as a potent anticholinergic agent. Structurally, it closely resembles atropine but possesses distinct pharmacological properties that make it particularly effective for specific therapeutic applications. The primary clinical use of scopolamine hydrobromide is the prevention and treatment of nausea and vomiting associated with motion sickness. It is frequently administered via transdermal patches applied behind the ear, providing sustained release over several days to maintain therapeutic blood levels without frequent dosing. Beyond motion sickness, the drug is also employed in anesthesia premedication to reduce salivary and bronchial secretions, thereby ensuring clearer airways during surgical procedures. Additionally, it plays a role in managing certain gastrointestinal spasms and irritable bowel syndrome due to its ability to inhibit smooth muscle contractions. In laboratory settings, scopolamine hydrobromide is extensively used as a tool compound to study cholinergic neurotransmission and cognitive functions. Researchers utilize it to induce amnesia or alter memory consolidation processes, offering insights into the mechanisms of learning and forgetting. Despite its utility, the compound carries significant side effects including dry mouth, blurred vision, drowsiness, and confusion, particularly in elderly patients. Its mechanism involves blocking acetylcholine receptors in the central and peripheral nervous systems, effectively disrupting parasympathetic nerve impulses. While highly effective when used correctly, strict adherence to dosage guidelines is essential to avoid toxicity. Regulatory bodies classify it as a prescription medication in most jurisdictions, emphasizing the need for professional medical supervision. As a versatile pharmaceutical agent, scopolamine hydrobromide remains a cornerstone in treating vestibular disorders and a critical reagent in neuropharmacological research, bridging clinical therapy with scientific discovery through its unique interaction with the human nervous system.
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