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CAS NO:
58546-56-8
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Basic Info
CAS Number
58546-56-8
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Schisantherin A is a potent lignan derivative isolated primarily from the fruits of *Schisandra chinensis* and *Schisandra sphenanthera*, plants renowned in traditional Chinese medicine for their hepatoprotective and adaptogenic properties. Chemically, this compound features a complex dibenzocyclooctadiene skeleton characterized by multiple methoxy and hydroxyl groups attached to its rigid ring structure. Its molecular formula is C25H30O9, reflecting a high degree of oxygenation that contributes significantly to its biological reactivity. The specific CAS registry number assigned to Schisantherin A is 18467-89-3, which serves as a unique identifier for researchers and regulatory bodies globally to ensure precise chemical tracking and standardization in pharmaceutical applications.
In the realm of pharmacological research, Schisantherin A has garnered substantial attention for its multifaceted therapeutic potential. It exhibits strong antioxidant activity by scavenging free radicals and enhancing the expression of endogenous antioxidant enzymes such as superoxide dismutase and glutathione peroxidase. This mechanism makes it particularly valuable in mitigating oxidative stress-induced cellular damage. Furthermore, extensive studies indicate its efficacy in protecting liver cells against toxins, including carbon tetrachloride and acetaminophen, by inhibiting inflammatory pathways and reducing hepatic enzyme leakage. Beyond hepatoprotection, emerging evidence suggests neuroprotective effects, where Schisantherin A may alleviate cognitive decline and neuronal apoptosis associated with ischemic injuries or neurodegenerative disorders.
The compound also demonstrates anti-inflammatory properties by suppressing pro-inflammatory cytokines like TNF-alpha and IL-6, offering promise in managing chronic inflammatory conditions. Due to these diverse bioactivities, Schisantherin A is increasingly explored as a lead candidate for developing novel drugs targeting liver diseases, neurological disorders, and metabolic syndromes. While currently utilized mainly in dietary supplements and herbal extracts within Asia, ongoing clinical investigations aim to validate its safety profile and efficacy for broader international pharmaceutical markets. Standardization of extraction methods remains crucial to maintain consistent potency, given the sensitivity of its chemical structure to environmental factors. As research advances, Schisantherin A stands poised to become a significant player in natural product-based therapeutics, bridging ancient medicinal wisdom with modern scientific validation.
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