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Basic Info
CAS Number
20874-52-6
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Saikosaponin D is a prominent bioactive triterpenoid saponin isolated primarily from the roots of *Bupleurum chinense* and *Bupleurum falcatum*, plants widely utilized in traditional Chinese medicine. With the Chemical Abstracts Service (CAS) registry number 20553-14-8, this compound features a complex molecular structure characterized by a dammarane-type skeleton. Its molecular formula is C42H68O13, corresponding to a molecular weight of approximately 784.99 g/mol. As a glycoside, Saikosaponin D consists of an aglycone core linked to sugar moieties, which significantly influences its solubility and biological activity profile.
In terms of pharmacological applications, Saikosaponin D has garnered substantial scientific attention for its diverse therapeutic potentials. It is extensively studied for its potent anti-inflammatory properties, demonstrating the ability to inhibit pro-inflammatory cytokines such as TNF-α and IL-6, making it a candidate for treating inflammatory disorders like hepatitis and arthritis. Furthermore, research indicates significant hepatoprotective effects, where the compound helps mitigate liver injury induced by toxins or oxidative stress. Beyond liver health, Saikosaponin D exhibits notable immunomodulatory activities, enhancing immune system regulation while also showing promise in anti-tumor research by inducing apoptosis in various cancer cell lines. Additionally, studies suggest potential antiviral capabilities against specific viral infections.
Currently, Saikosaponin D serves as a critical reference standard in pharmaceutical quality control and analytical chemistry laboratories. Due to its high purity requirements, it is frequently employed in HPLC and LC-MS assays to ensure the consistency and efficacy of herbal extracts containing *Bupleurum* species. While natural sources provide the primary origin, semi-synthetic methods are increasingly explored to meet the growing demand for research-grade material. Despite its promising benefits, clinical translation requires further rigorous trials to establish optimal dosing and safety profiles. Overall, Saikosaponin D remains a vital compound bridging traditional herbal wisdom and modern pharmacological innovation, offering valuable insights into novel drug development for inflammation, liver diseases, and oncology.
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